This roll-on is formulated for topical neuroregulatory support in individuals experiencing:

• Major depressive episodes (mild to moderate).
• Generalized Anxiety Disorder (GAD).
• Emotional instability, panic episodes, or stress-induced dysregulation.
• Sleep disturbances and fatigue associated with mood disorders.
• Nervous system exhaustion or adrenal dysregulation.

The blend targets central nervous system (CNS) neurochemistry, hypothalamic-pituitary-adrenal (HPA) axis modulation, autonomic tone, and limbic region function—aiming to improve emotional resilience, mood stability, and nervous system regulation.

Depression and anxiety are complex, neurobiological conditions involving imbalances in key neurotransmitters such as serotonin, dopamine, norepinephrine, and GABA. These conditions often overlap and involve:

• Hyperactivation of the amygdala (emotional center).
• Reduced prefrontal cortex regulation (executive function and mood control).
• Dysregulation of the HPA axis, leading to excess cortisol.
• Parasympathetic nervous system suppression, impairing rest and recovery.
• Neuroinflammation and mitochondrial dysfunction in chronic states.

This roll-on blend supports correction of these dysfunctions through transdermal absorption of neuroactive essential oils.

Recommendation: we suggest using this blend with our Depression support blend internally and our depression and anxiety diffuser oil, trauma diffuser oil were needed. Also, our depression herbal capsules if needed.

Recommended for:

• Adults and children with mood or stress-related symptoms.
• Individuals with chronic stress, emotional exhaustion, or nervous tension.
• Patients on antidepressants or anxiolytics (as adjunct topical support).
• Women with PMS/PMDD, postpartum mood swings, or menopausal mood instability.
• Individuals with difficulty sleeping due to nervous hyperarousal.

Cautions:

• Avoid during the first trimester of pregnancy (due to hormonal sensitivity).
• Not a replacement for medical treatment in severe psychiatric illness.

Clinical Use Cases

• Mild to moderate depression.
• Anxiety with physical symptoms (racing heart, tremors, breath-holding).
• Panic attacks (used during episodes).
• Menopausal or hormonal emotional instability.
• Stress-related digestive disturbances (when nervous system is involved).
• Emotional trauma recovery (adjunct support).
• Adrenal fatigue / nervous exhaustion.
• Sleep disruption due to stress.
• Postpartum mood swings (non-severe).

The Depression and Anxiety Roll-On (10 ml) is a natural designed, neuroactive topical formulation that modulates key neurotransmitters and hormonal stress pathways. By influencing GABA, serotonin, dopamine, and the HPA axis through transdermal delivery, this blend helps restore emotional equilibrium, nervous system stability, and mood resilience. It is appropriate for both acute emotional regulation and daily mood support when used as part of a broader wellness strategy.