Bilberry: Enriched with anthocyanosides, it supports brain health in KPU-related disorders by fortifying the body’s natural defense against oxidative stress and inflammation. Its role in reinforcing the Blood-brain barrier
empowers resilience against neurodegenerative diseases.

Borage: Abundant in GLA, it nurtures neurotransmitter balance and physiological function, empowering the body’s inherent abilities in managing symptoms of KPU-related disorders like schizophrenia and bipolar disorder.

Evening Primrose: High GLA concentration harnesses anti-inflammatory benefits, supporting the body’s natural response to conditions like schizophrenia and bipolar disorder. Collaboration with key vitamins enhances cognitive function in ADHD and sleep disorders.

Folic Acid: Critical for neural development, its inclusion supports the body’s natural capacity for improved cognitive function and neuroprotection in KPU-related disorders.

GABA: Integral to neurotransmission, it aids in maintaining a balanced neurotransmitter system, supporting the body’s innate ability for brain health and symptom management in KPU-related disorders.

L-Lysine: Addresses deficiencies impacting Vit B6 activity, empowering the body’s natural cognitive function in disorders like schizophrenia, bipolar disorder, and ADHD.

Magnesium: Crucial for brain health, it counters elevated Vitamin B6 levels and acts as a muscle relaxant, supporting the body’s natural response to alleviate symptoms common in KPU-related disorders.

Moringa: Rich in antioxidants, it supports neuroprotection, aiding the body’s natural defense against diverse health issues. Valuable for individuals with KPU-related disorders. Antioxidant. Anti-Inflammatory. Contains 90-plus vitamins, minerals, and amino acids. Moringa has almost 540 compounds that can treat about 300 health issues and is considered a ‘super-food’.

7x more Vitamin C than oranges

17x more calcium than milk

9x more protein than yoghurt

15x more potassium than bananas

25x more iron than spinach

About 6 spoons of moringa leaf powder can meet a woman’s daily iron and calcium requirements during pregnancy.

Moringa powder can be a substitute for iron tablets to treat anaemia. Beef has only 2mg of iron, while moringa powder has 28mg.

It contains all nine essential amino acids.

100mg of Moringa contains amongst many others, the following required for KPU:

473mg Magnesium, 8.2mg Niacin, 0.8mg Thiamine, 5mg Manganese

Rich in Vit A, B1, B2, B3, B6, C, E, K & Zinc

N-Acetylcysteine (NAC): Effective in mental health, it reduces oxidative stress and inflammation, supporting the body’s natural ability to manage disorders like schizophrenia and bipolar disorder.

Pumpkin Seed: Rich mineral and antioxidant content provides neuroprotective effects, supporting the body’s natural response to conditions associated with KPU.

Slippery Elm: Supports mucosal health, addressing the gut-brain connection, and enhancing the body’s natural ability to tackle digestive disorders in individuals with KPU-related disorders.

Vitamin B3 (Niacin): Accelerates Pyrroluria recovery, potentially benefiting conditions like schizophrenia, bipolar disorder, and ADHD, cleverly supporting the body’s oxygen supply to the brain. Speeds up Pyrroluria recovery process. Serotonin, the “happy neurotransmitter”, needs Niacin. Serotonin is made from the amino acid tryptophan, but only in the presence of Niacin (Vit B3).

Vitamin B3 is needed for the brain to make use of essential fats. Vit B3, through its flushing action, improves oxygen supply to the brain. Niacin is used for acute Schizophrenia. It stops the brain from producing adrenochrome from Adrenalin (a chemical known for causing hallucinations)
It works with Vit B12 and Folic Acid to keep adrenalin and noradrenalin levels in balance and prevents abnormal production of adrenochrome in the brain. Niacin is essential to produce Tryptophan, which makes serotonin. Nicotinamide (another form of Vit B3) is often used as it does not create a ‘skin flushing’ effect.

Vitamin C Palmitate: Accumulates in the central nervous system, contributing to neuroprotection. Potential benefits in mitigating oxidative stress in the brain for individuals with KPU-related disorders, cleverly supporting the body’s overall brain health.

Vitamin B6: Multifaceted role in brain health, influencing neurotransmitter synthesis, amino acid metabolism, and haem synthesis. Crucial for managing KPU-related disorders and supporting the body’s overall health. Deficiency can cause anxiety, insomnia, irritability, and muscle weakness.

The first step in haem synthesis is Vit B6-dependent. Without haem haemoglobin synthesis is compromised, and subsequently oxygen transport. The first step in haem synthesis occurs in the mitochondria (responsible for energy production). There is a strong connection between Kryptopyrroluria and mitochondrial disorders.

Depression of haem production can lead to serious metabolic defects; this is why some cases of anaemia are persistent and do not respond to iron supplements.

Vit B6 plays a significant part in the methylation cycle, the metabolism of amino acids, and the synthesis of neurotransmitters. Vit B6 is necessary for the conversion of Glutamate to GABA. Glutamate is an excitatory neurotransmitter beneficial for learning, while GABA is a calming neurotransmitter, essential for speech.

In KPU, this conversion is disrupted due to Vit B6 deficiency, which causes high levels of Glutamate, which can deplete Glutathione (a major antioxidant) for detoxification, causing a compromised Gut lining.

Zinc Picolinate: Essential for enzyme functionality, DNA stabilization, and immune support. Crucial for individuals with KPU-related disorders, cleverly supporting the body’s comprehensive management against a spectrum of symptoms.