How the Kidneys and Bladder work

The kidneys are bean-shaped organs responsible for filtering blood, removing waste products, and regulating electrolytes. They produce urine, which flows through two thin tubes called ureters into the bladder.

The bladder, a muscular sac, stores urine until it’s expelled through the urethra during urination. This complex system ensures the elimination of waste and excess fluids, maintaining a delicate balance crucial for overall health. The kidneys also play a role in controlling blood pressure, producing red blood cells, and activating vitamin D for bone health.

Kidney & Bladder disorders

• Urinary Tract Infection (UTI): Infection affecting any part of the urinary system, including the kidneys, bladder, and urethra.
• Kidney Stones: Hard deposits formed in the kidneys from minerals and salts, causing pain and potential blockages.
• Chronic Kidney Disease (CKD): Gradual loss of kidney function over time, often due to conditions like diabetes or high blood pressure.
• Interstitial Cystitis (IC): Chronic inflammation of the bladder wall, leading to pain and discomfort.
• Polycystic Kidney Disease (PKD): Genetic disorder causing fluid-filled cysts to form in the kidneys, potentially leading to kidney failure.
• Bladder Cancer: Uncontrolled cell growth in the bladder, often associated with blood in the urine.
• Kidney Infection (Pyelonephritis): Serious infection of the kidneys, usually resulting from an untreated urinary tract infection.
• Overactive Bladder (OAB): Condition causing a sudden urge to urinate, sometimes leading to urinary incontinence.
• Nephrotic Syndrome: Kidney disorder characterized by protein in the urine, low blood protein levels, high cholesterol, and swelling.
• Bladder Stones: Hardened mineral deposits in the bladder, causing pain and potential blockages.
• Renal Failure: Severe impairment or loss of kidney function, requiring medical intervention or dialysis.
• Urethral Stricture: Narrowing of the urethra, impacting the flow of urine.
• Hematuria: Presence of blood in the urine, often a symptom of an underlying kidney or bladder issue.
• Hydronephrosis: Swelling of one or both kidneys due to a backup of urine.
• Prostatitis: Inflammation of the prostate gland, which can affect urinary function.

Symptoms of Kidney & Bladder problems

• Pain or Discomfort: Symptoms of kidney and bladder disorders often involve pain or discomfort, such as flank pain for kidneys and pelvic pain or pain during urination for the bladder.
• Urinary Changes: Common urinary changes include alterations in frequency, urgency, and the presence of hematuria.
• Abdominal Issues: Disorders may manifest with abdominal symptoms like swelling, fluid retention, and abdominal pain.
• Disruptions in Urinary Function: Kidney and bladder issues can lead to disruptions in urinary function, including difficulty starting or maintaining urination, painful urination, and incomplete bladder emptying.
• General Health Changes: Individuals may experience changes in general health, such as fatigue, weakness, unexplained weight loss, and loss of appetite.
• Appearance Changes: Changes in appearance, such as pale skin or pallor, and characteristics of urine like dark, foamy, or bubbly appearance, may indicate kidney or bladder issues.
• Systemic Symptoms: Systemic symptoms can include fever, chills, nausea, and vomiting, which may be indicative of a broader health concern.
• Specific Symptoms for Kidney Stones: Kidney stones can cause severe back or side pain, radiating pain to the lower abdomen and groin, and painful urination.
• Symptoms of Bladder Infection (Cystitis): Bladder infections may present with increased frequency of urination, burning or pain during urination, and a strong urge to urinate.
• Symptoms of Kidney Infection (Pyelonephritis): Kidney infections may involve high fever, back pain, nausea, vomiting, and cloudy or foul-smelling urine.
• Symptoms of Overactive Bladder (OAB): Overactive bladder may manifest as sudden, strong urges to urinate and incontinence, where individuals cannot control urine flow.

It is essential to seek medical attention if experiencing any of these symptoms, as they may indicate an underlying kidney or bladder issue that requires diagnosis and appropriate treatment

The role of Candida in Kidney & Bladder problems

Candida and other fungi can play a role in kidney and bladder problems by causing infections. In the urinary tract, Candida, a type of yeast, can lead to a condition known as fungal urinary tract infection (UTI). These infections can affect the bladder, ureters, and kidneys. The overgrowth of Candida in the urinary tract can be triggered by factors such as a weakened immune system, antibiotic use, or conditions that promote fungal growth.

Candida can adhere to the lining of the urinary tract, leading to irritation, inflammation, and potential damage to the tissues. Symptoms of a fungal UTI may include pain or a burning sensation during urination, frequent urination, lower abdominal discomfort, and cloudy or foul-smelling urine.

In severe cases, if the infection spreads to the kidneys, it can result in more significant health issues, including kidney infections (pyelonephritis). Kidney infections can cause symptoms such as back pain, fever, nausea, and vomiting.

Which hormones and enzymes play a role in kidney & bladder health and how is it connected to the adrenals?

Several hormones and enzymes play critical roles in kidney and bladder health, and their connection to the adrenals is integral to maintaining overall renal well-being. Here are key factors involved:

• Renin-Angiotensin-Aldosterone System, abbreviated as RAAS:This hormonal system regulates blood pressure and fluid balance. Renin, released by the kidneys, converts angiotensinogen into angiotensin I, which is then converted to angiotensin II. Angiotensin II stimulates the release of aldosterone from the adrenal glands, promoting sodium and water retention, and potassium excretion. The balance of these electrolytes is crucial for kidney function and overall fluid balance
• Antidiuretic Hormone (ADH or Vasopressin): Produced by the hypothalamus and released by the pituitary gland, ADH acts on the kidneys to regulate water reabsorption. It plays a key role in maintaining water balance, preventing excessive fluid loss through urine.
• Cortisol: Produced by the adrenal glands, cortisol has anti-inflammatory effects and influences blood pressure. In times of stress, cortisol levels rise, potentially affecting blood pressure regulation and contributing to kidney health challenges.
• Aldosterone: Released by the adrenal glands, aldosterone promotes sodium retention and potassium excretion in the kidneys. This hormone is crucial for maintaining electrolyte balance and blood pressure.
• Enzymes in Glucose Metabolism: Glucose regulation is essential for kidney health. Enzymes like aldose reductase and sorbitol dehydrogenase are involved in pathways that can impact kidney function, particularly in conditions like diabetes where glucose metabolism is altered.
• Renal Enzymes: Various enzymes, including those involved in the metabolism of nutrients and waste products, are essential for normal kidney function. Disruptions in these enzymatic processes can lead to kidney disorders.The adrenal glands, situated on top of each kidney, play a pivotal role in responding to stress and contributing to the regulation of fluid balance and electrolytes. The hormones produced by the adrenals, especially cortisol and aldosterone, have direct effects on the kidneys.Imbalances in these hormones can influence blood pressure, fluid regulation, and electrolyte balance, potentially contributing to kidney and bladder health issues.Maintaining a healthy endocrine system, including the adrenal glands, is crucial for supporting kidney and bladder function. Factors such as stress management, proper hydration, and a balanced diet contribute to overall endocrine and renal well-being. 

   

  Ingredients which are traditionally used for this disorder
  Technical info:

  African Potato: The immunomodulatory effects of African Potato, driven by beta-sitosterol and campesterol, make it a potential adjunct in conditions requiring immune support. Its impact on immune cells, particularly T-cells, warrants consideration for patients with immunological challenges.

  Agrimony: Rich in tannins and flavonoids, agrimony’s astringent and anti-inflammatory properties can aid in bladder control and alleviate symptoms associated with kidney disorders. Its potential modulation of immune responses adds to its therapeutic profile.

  Aloe: Aloe’s active compounds, such as aloin and aloe-emodin, contribute to its laxative effects, making it valuable in conditions requiring gentle bowel regulation. The presence of acemannan enhances its immune-modulating properties.

  Apple Cider Vinegar: Acetic acid in apple cider vinegar plays a role in dissolving kidney stones, while its potassium content contributes to fluid balance. This makes it a potential supportive measure for individuals prone to stone formation.

  Astragalus: With polysaccharides, isoflavonoids, and saponins, astragalus exhibits adaptogenic, anti-inflammatory, and immune-modulating effects. These properties position it as a complementary approach in managing kidney disorders and supporting overall immune health.

  Basil: Eugenol, the active compound in basil, offers anti-inflammatory and analgesic effects, potentially assisting in dissolving kidney stones and alleviating associated pain. Its inclusion may be considered in pain management strategies.

  Bearberry: Arbutin, converted to hydroquinone, provides bearberry with antibacterial and diuretic properties. This makes it a candidate for urinary tract infections and kidney support, particularly against E. coli.

  Bilberry: Anthocyanosides in bilberry contribute antioxidant and anti-inflammatory effects, suggesting potential benefits in kidney diseases. Its ability to inhibit E. coli adhesion aligns with its broader antimicrobial properties.

  Buchu: Diosphenol, quercetin, and rutin in buchu confer anti-inflammatory, antioxidant, and antimicrobial actions. Its diuretic properties support kidney and urinary tract health, making it relevant for infections and inflammation.

  Celery Seed: Volatile oils like limonene and coumarins in celery seed contribute to its diuretic and anti-inflammatory effects, offering potential relief in kidney health and stone prevention.

  Cornsilk: Cornsilk’s mucilage, tannins, and bioflavonoids contribute to its soothing, antimicrobial, and diuretic properties. Its potential to strengthen tissues and address urinary tract issues broadens its application.

  Dandelion: Dandelion’s bitter constituents, including sesquiterpene lactones, support liver and kidney function. Rich in vitamins and minerals, it provides comprehensive nutritional support for overall well-being.

  Golden Rod: Active compounds like saponins and flavonoids in goldenrod offer anti-inflammatory, diuretic, and immune-stimulating effects. These properties position it as a potential ally in kidney health and immune support.

  Hibiscus: Polyphenols in hibiscus, such as anthocyanins, contribute antioxidant and anti-inflammatory effects, making it valuable in kidney stone prevention and overall renal health.

  Horse Chestnut: Aescin, the active compound, provides anti-inflammatory and analgesic effects, offering relief in conditions associated with kidney stones. Its potential impact on ureter swelling aids in stone passage.

  Horsetail: Silicic acid and flavonoids in horsetail offer diuretic, anti-inflammatory, and antioxidant effects, supporting kidney health and connective tissue strength. Its potential in managing urinary tract infections is noteworthy.

  Hydrangea Root: Inhibiting TH17 cells, hydrangea root showcases anti-inflammatory properties, making it relevant in conditions where immune modulation is beneficial. Its support in expelling urinary calculi contributes to kidney health.

  L-Arginine: L-arginine’s role in urinary citrate and calcium oxalate levels, mediated by nitric oxide production, hints at its potential cardiovascular and renal benefits. Its involvement in preventing renal epithelial damage adds to its significance.

  Liquorice Root: Glycyrrhizin in liquorice root influences cortisol-cortisone balance, affecting sodium/potassium regulation. Its anti-inflammatory properties contribute to adrenal support and overall kidney health.

  Magnesium: Beyond its role in preventing bladder spasms, magnesium’s influence on muscle and nerve function supports kidney health and electrolyte balance. Its potential in reducing oxidative stress is relevant in renal protection.

  Milk Thistle: Silymarin’s hepatoprotective effects make milk thistle valuable in detoxification, indirectly benefiting kidney function. Its antioxidant properties contribute to cellular protection.

  N-Acetyl-Cysteine: NAC’s replenishment of glutathione levels confers antioxidant effects, providing renal protection against oxidative stress. Its potential in reducing lead poisoning aligns with broader environmental stress mitigation.

  Omega 3: Omega-3’s anti-inflammatory effects, attributed to EPA and DHA, contribute to overall renal health. Its potential in reducing inflammation supports kidney function.

  Pomegranate: Polyphenols and antioxidants in pomegranate offer renal protection, preventing kidney stone formation and supporting overall urinary health. Its acidity-modulating effects are relevant in stone prevention.

  Potassium: Essential for fluid balance and electrolyte regulation, potassium plays a role in preventing kidney stone formation and maintaining renal health.

  Selenium: Selenium’s role in adrenal function and antioxidant protection adds to its relevance in kidney health. Its support in reducing oxidative stress contributes to cellular well-being.

  Tribulus Terrestris: With the potential to lower phosphate levels and dissolve stones, tribulus terrestris offers urinary health support. Its role in inhibiting stone formation aligns with its overall kidney benefits.

  Vitamin A: Vitamin A’s involvement in renal health, particularly in preventing kidney stone formation, underscores its significance. Its support in maintaining mucosal integrity adds to its renal benefits.

  Vitamin B12: Addressing adrenal insufficiency, vitamin B12 contributes to overall adrenal health, indirectly impacting kidney function. Its role in neurotransmitter synthesis aligns with broader neurological support.

  Vitamin B5: Participating in adrenal function, vitamin B5 supports adrenal health and, by extension, kidney function. Its role in stress response modulation is noteworthy.

  Vitamin B6: Vitamin B6’s influence on reducing kidney stone risk and supporting overall kidney health highlights its importance. Its participation in amino acid metabolism contributes to broader renal function.

  Vitamin C: While vitamin C is essential, high doses can increase kidney stone risk. Careful consideration of dosage is crucial. Its antioxidant effects, when balanced, support overall renal health.

  Vitamin D3: Addressing bedwetting and incontinence, vitamin D3’s impact on pelvic floor function and neurological modulation contributes to urinary health.

  Vitamin E: Vitamin E’s inhibition of calcium oxalate crystal formation supports kidney health and prevents stone formation.

  Zinc: Zinc’s influence on crystal growth and immune function highlights its importance in kidney health, with potential benefits against oxidative stress.